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Table 1 Tumor characteristics

From: Follicular thyroid carcinoma: differences in clinical relevance between minimally invasive and widely invasive tumors

Characteristics MI-FTC WI-FTC p
42 29
Suspect of malignancy by cytology (pre-op) 30 (71.4 %)a 15 (51.7 %)b 0.133
Tumor size (mm), mean ± SD 27.05 ± 11.52 39.34 ± 15.44 0.000
  Range 6–52 16–75  
  Median (95 % CI) 26 (23.57–30.53) 38 (33.72–44.96)  
Tumor size ≤ 1.0 cm 4 (9.5 %) 0 0.140
Tumor size > 1.0 cm ≤ 2.0 9 (21.4 %) 2 (6.8 %) 0.180
Tumor size > 2.0 cm ≤ 4.0 25 (59.6 %) 15 (51.8 %) 0.628
Tumor size > 4 cm 4 (9.5 %) 12 (41.4 %) 0.003
Pathologic association    
  Multinodular goiter 13 (30.9 %) 10 (34.6 %) 0.800
  Hashimoto’s thyroiditis 13 (30.9 %) 5 (17.2 %) 0.269
  Graves’ disease 1 (2.4 %) 0 0.851
  Normal thyroid 15 (35.8 %) 14 (48.2 %) 0.332
  Follicular thyroid adenoma 1 (2.4 %) 0 0.851
  Papillary microcarcinoma 6 (14.3 %) 3 (10.3 %) 0.729
Multifocality 0 2 (6.8 %) 0.163
Thyroid capsular invasion 0 1 (3.4 %) 0.408
Vascular invasion 9 (21.4 %) 15 (51.8 %) 0.011
Extra thyroid invasion 0 1 (3.4 %) 0.408
Lymph node metastasis 0 5 (17.2 %) 0.009
Well/Poorly differentiated 0 2 (6.8 %) 0.163
M1 at diagnosis 0 0
Concomitant parathyroid cancer 1 (2.4 %) 0 0.851
  1. MI-FTC minimally invasive - follicular thyroid carcinoma, WI-FTC widely invasive - follicular thyroid carcinoma, SD standard deviation, CI confidence interval, M1 metastasis to distant sites
  2. aMI-FTC: 28 Thy 3, 2 Thy 4
  3. bWI-FTC: 13 Thy 3, 2 Thy 4