Fig. 1

a Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) immunohistochemical (IHC) analysis showed protein expression in 80 % of cancer cells. Arrows indicate tumor cells with positive staining and reference staining in stromal cells. b PTEN IHC analysis showed protein expression in less than 80 % of cancer cells. Arrows indicate tumor cells with an absence of staining and positively stained stromal