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Table 1 Clinical features of reported cases of AFP-producing colorectal carcinomas

From: Alpha-fetoprotein-producing early rectal carcinoma: a rare case report and review

Case

Author

Age/gender

Location

Pretherapy AFP level (ng/ml)

Macroscopic classification

Depth of invasion

Lymph node metastasis

Pretherapy Metastases

Histology

Prognosis

1

Nakajima et al. [7]

50/M

R

3,018

NS

Prostate

+

Liver/lung

Mod-por

5M dead

2

Yu et al. [8]

54/M

R

5,126

Ulcerated

Serosal

+

Liver

Well

0M dead

3

Sato et al. [9]

43/M

R

7,060

Ulcerated

Extraserosal

+

Liver

Well-mod

4M dead

4

Hocking et al. [10]

39/F

S/C

7,200

NS

Perforation

+

Liver

a

1M dead

5

Kato et al. [11]

75/M

C

3,070

Ulcerated

NS

+

No

Por

4M dead

6

Taguchi et al. [12]

71/M

R

220,000

Ulcerated

Muscular

-

No

b

12M dead

7

Kurihara et al. [13]

67/M

T/C

10,978

Ulcerated

Serosal

+

Liver

Por

NS

8

Ishikura et al. [14]

48/F

S/C

6,600

Ulcerated

Subserosal

NS

Liver

Well

4M dead

9

Lattes et al. [15]

41/M

R

NS

Ulcerated

NS

+

Liver

Well-muc-sig

12M alive

10

Yachida et al. [16]

59/M

T/C

12,873

Ulcerated

Serosal

-

Liver

Well

2M dead

11

Fu et al. [17]

71/M

T/C

318

Ulcerated

Subserosal

-

No

Por

5Y alive

12

Present case

41/F

R

2

Elevated

Submucosal

-

No

Mod-por

2M alive

  1. AFP = alpha-fetoprotein; NS = not stated; C = cecum; S/C = sigmoid colon; T/C = transverse colon; R = rectum; well = well differentiated adenocarcinoma; mod = moderately differentiated adenocarcinoma; por = poorly differentiated adenocarcinoma; muc = mucinous adenocarcinoma; sig = signet-cell-carcinoma; aAdenocarcinoma showing hepatoid morphology; bglandular differentiation consisted of columnar cancerous cells.