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Table 1 Clinical and pathological data

From: Tumor regression in rectal cancer after intensified neoadjuvant chemoradiation: a morphometric and clinicopathological study

  DRG0 DRG1 DRG2 DRG3 DRG4
Tumor location      
 Upper rectum 0 2 3 0 0
 Middle rectum 1 15 20 6 2
 Lower rectum 0 13 24 11 7
Type of surgery      
 Anterior resection 1 24 32 8 7
 Amputation 0 6 15 9 2
UICC TNM stage      
 Stage 0 0 0 0 0 6
 Stage I 0 6 9 6 0
 Stage II 0 8 8 5 0
 Stage III 1 13 17 3 1
 Stage IV 0 3 13 3 2
Depth of infiltration by ypT      
 ypT0 0 0 0 0 9
 ypT1 0 1 1 4 0
 ypT2 0 6 12 6 0
 ypT3 1 21 34 7 0
 ypT4 0 2 0 0 0
Depth of extramural extension, vital tumor      
 None 0 7 13 10 9
 Early (<3 mm) 0 2 10 5 0
 Progressed (3 to 10 mm) 1 16 19 2 0
 Deep (>10 mm) 0 5 5 0 0
Nodal status (ypN)      
 ypN0 0 15 20 13 7
 ypN1 1 7 17 3 1
 ypN2 0 8 10 1 1
Lymphatic spread (L)      
 Absent 0 25 43 17 9
 Present 1 5 4 0 0
Venous angioinvasion (V)      
 Absent 0 21 37 15 8
 Present 1 9 10 2 1
Perineural spread (Pn)      
 Absent 0 24 41 17 8
 Present 1 6 6 0 1
Distance towards CRMa,b      
 >3 mm 1 22 35 17 8
 1 to 3 mm 0 4 5 0 0
 <1 mm 0 4 6 0 1
Local recurrence      
 Negative 1 28 40 14 9
 Positive 0 2 6 2 0
Death of disease      
 Negative 0 23 22 12 8
 Positive 1 7 24 4 1
  1. aCRM, circumferential resection margin; bMeasurement not possible for technical reasons in one case. DRG, Dworak regression grade.