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Table 1 Clinical and pathological data

From: Tumor regression in rectal cancer after intensified neoadjuvant chemoradiation: a morphometric and clinicopathological study

 

DRG0

DRG1

DRG2

DRG3

DRG4

Tumor location

     

 Upper rectum

0

2

3

0

0

 Middle rectum

1

15

20

6

2

 Lower rectum

0

13

24

11

7

Type of surgery

     

 Anterior resection

1

24

32

8

7

 Amputation

0

6

15

9

2

UICC TNM stage

     

 Stage 0

0

0

0

0

6

 Stage I

0

6

9

6

0

 Stage II

0

8

8

5

0

 Stage III

1

13

17

3

1

 Stage IV

0

3

13

3

2

Depth of infiltration by ypT

     

 ypT0

0

0

0

0

9

 ypT1

0

1

1

4

0

 ypT2

0

6

12

6

0

 ypT3

1

21

34

7

0

 ypT4

0

2

0

0

0

Depth of extramural extension, vital tumor

     

 None

0

7

13

10

9

 Early (<3 mm)

0

2

10

5

0

 Progressed (3 to 10 mm)

1

16

19

2

0

 Deep (>10 mm)

0

5

5

0

0

Nodal status (ypN)

     

 ypN0

0

15

20

13

7

 ypN1

1

7

17

3

1

 ypN2

0

8

10

1

1

Lymphatic spread (L)

     

 Absent

0

25

43

17

9

 Present

1

5

4

0

0

Venous angioinvasion (V)

     

 Absent

0

21

37

15

8

 Present

1

9

10

2

1

Perineural spread (Pn)

     

 Absent

0

24

41

17

8

 Present

1

6

6

0

1

Distance towards CRMa,b

     

 >3 mm

1

22

35

17

8

 1 to 3 mm

0

4

5

0

0

 <1 mm

0

4

6

0

1

Local recurrence

     

 Negative

1

28

40

14

9

 Positive

0

2

6

2

0

Death of disease

     

 Negative

0

23

22

12

8

 Positive

1

7

24

4

1

  1. aCRM, circumferential resection margin; bMeasurement not possible for technical reasons in one case. DRG, Dworak regression grade.