Severity of liver cirrhosis: a key role in the selection of surgical modality for Child-Pugh A hepatocellular carcinoma

Table 1 Long-term outcomes of LR in recent studies with comparative analyses of cirrhosis status

Authors	Cirrhosis status	Patients ( n )	Overall survival (%)	P value
Taura et al. [20]	Non-cirrhosis	127	81	<0.001
	Child A cirrhosis	129	54
	Child B cirrhosis	37	28
Gassmann et al. [32]	Normal liver	21	50	0.032
	Fibrosis (Batts system)	27	28
	Cirrhosis	24	17
Huang et al. [33]^§	Mild cirrhosis	29	74.3	0.001
	Moderate cirrhosis	29	48.1
	Severe cirrhosis	19	26.7
Santambrogio et al. [28]	Child A cirrhosis without PH	160	65	0.024
	Child A cirrhosis with PH	63	48	0.024
Kadri et al. [29]	Ishak stages 1 to 2	45	68.9	0.09
Kadri et al. [29]	Ishak stages 3 to 6	155	56.8	0.09
Roayaie et al. [25]	Fibrosis (METAVIR 0 to 3)	38	84	NS
	Cirrhosis (METAVIR 4)	89	63	NS
Wang et al. [26]	Fibrosis (Ishak 1 to 5)	135	73	0.01
	Cirrhosis (Ishak 6)	54	50	0.01
Kim et al. [19]^§	F3-F4B (Laennec system)	82	91.4	0.007
	F4C (Laennec system)	10	70	0.007

The overall survivals indicate the 5-year overall survival rates, except ^§ which indicates the 3-year overall survival rate. PH, portal hypertension; NS, not significant.

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