Poorly differentiated clusters with larger extents have a greater impact on survival: a semi-quantitative pathological evaluation for 239 patients with non-mucinous pT2-3 colorectal carcinoma

Table 3 Univariate and multivariate survival analyses of representative histopathological variables

Parameters	Univariate	Multivariate
Parameters	Univariate	Hazard ratio	95% CI	P value
Age (≥65 vs. <65)	0.55	1.02	0.54 to 1.91	0.9495
Tumor location (colon vs. rectum)	0.80	1.16	0.61 to 2.21	0.6517
Depth (pT3 vs. pT2)	0.38	1.19	0.56 to 2.53	0.6463
Lymph node involvement (pN1-2 vs. pN0)	0.036	1.35	0.70 to 2.60	0.3758
PDC grade (G3 vs. G1-2)	<0.0001	3.21	1.67 to 6.20	<0.0005

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