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Table 1 Relationship of preoperative plasma fibrinogen level with clinicopathological parameter

From: The clinical significance of preoperative plasma fibrinogen level and platelet count in resectable esophageal squamous cell carcinoma

Variable

N

Fibrinogen level

P value

Fibrinogen level

P value

  

Mean ± SD

 

Normal

Hyperfibrinogenemia

 

(g/L)

(1.5 to 4 g/L)

(≥4 g/L)

Gender

      

  Male

95

3.94 ± 0.98

0.034

51

44

0.252

  Female

24

3.48 ± 0.73

 

16

8

 

Age

      

  <60

59

3.7 ± 0.94

0.101

38

21

0.077

  ≥60

60

3.99 ± 0.95

 

29

31

 

Smoking history

      

  Yes

71

3.91 ± 0.95

0.371

29

19

0.457

  No

48

3.75 ± 0.96

 

38

33

 

Location

      

  Upper

15

3.56 ± 0.74

0.144

9

6

0.528

  Middle

67

3.78 ± 0.99

 

40

27

 

  Lower

37

4.08 ± 0.93

 

18

19

 

Tumor length

      

  <3.85 cm

64

3.56 ± 0.88

<0.001

42

22

0.027

  ≥3.85 cm

55

4.18 ± 0.93

 

25

30

 

Differentiation

      

  Well

33

3.94 ± 0.81

0.782

17

16

0.676

  Moderate

51

3.81 ± 1.09

 

31

20

 

  Poor

35

3.8 ± 0.87

 

19

16

 

Tumor stage

      

  T1

18

3.25 ± 0.68

0.001

15

3

0.013

  T2

26

3.67 ± 0.91

 

17

9

 

  T3

67

3.97 ± 0.92

 

33

34

 

  T4

8

4.69 ± 1.11

 

2

6

 

Lymph node status

      

  Negative

75

3.77 ± 0.94

0.267

46

29

0.149

  Positive

44

3.97 ± 0.97

 

21

23

 

Pathological stages

      

  I

21

3.48 ± 0.81

0.034

15

6

0.011

  II

58

3.79 ± 0.98

 

37

21

 

  III

40

4.12 ± 0.91

 

15

25

 

Adjuvant treatment

      

  None

71

3.87 ± 0.95

0.962

37

34

0.307

  Radiotherapy

25

3.83 ± 0.97

 

13

12

 

  Chemotherapy

11

3.9 ± 0.82

 

8

3

 

  CRT

12

3.72 ± 1.11

 

9

3

 

Recurrence

      

  Yes

81

3.94 ± 0.97

0.116

40

41

0.026

  No

38

3.65 ± 0.89

 

27

11

 
  1. SD, standard deviation; CRT, chemoradiotherapy. P < 0.05 is of significance.