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Table 2 Association between clinical pathological variables and SUVmax values

From: Associations between the standardized uptake value of 18F-FDG PET/CT and the prognostic factors of invasive lobular carcinoma: in comparison with invasive ductal carcinoma

  SUVmax
Total ( n = 105) ILC ( n = 32) IDC ( n = 73)
Mean ± SD Mean ± SD Mean ± SD
Median (interquartile range) Median (interquartile range) Median (interquartile range)
Cancer type (n = 105; 32, 73)a
 ILC (n = 32) 1.99 ± 1.72   
1.70 (0.50 to 3.05)
 IDC (n = 73) 3.91 ± 3.99   
2.30 (1.40 to 6.10)
P value 0.032   
Tumor Grade (n = 105; 32, 73)a
 Grade 1 (n = 35; 9, 26)a 2.07 ± 2.02 1.63 ± 1.36 2.22 ± 2.21
1.70 (1.10 to 2.40) 1.90 (0.00 to 2.40) 1.60 (1.20 to 2.30)
 Grade 2 (n = 53; 18, 35)a 2.97 ± 3.37 1.76 ± 1.54 3.59 ± 3.88
2.20 (1.00 to 3.60) 1.60 (0.00 to 3.20) 2.30 (1.20 to 5.30)
 Grade 3 (n = 17; 5, 12)a 7.02 ± 4.31 3.46 ± 2.46 8.51 ± 4.07
6.70 (4.50 to 8.40) 2.80 (1.50 to 5.30) 7.25 (6.05 to 11.90)
P value <0.001 0.393 < 0.001
ER (n = 104; 31, 73)a
 Negative (n = 20; 2, 18)a 5.84 ± 5.10 0.80 ± 1.13 6.39 ± 5.06
5.55 (1.90 to 7.85) 0.80 (0.00 to 1.60) 5.95 (2.30 to 8.40)
 Positive (n = 84; 29, 55)a 2.77 ± 2.83 2.14 ± 1.72 3.09 ± 3.23
1.95 (1.20 to 3.45) 1.80 (1.00 to 3.20) 2.10 (1.30 to 4.70)
P value 0.010 0.257 0.007
PR (n = 103; 31, 72)a
 Negative (n = 33; 5, 28)a 4.82 ± 5.00 0.92 ± 0.85 5.52 ± 5.11
2.30 (1.30 to 7.30) 1.30 (0.00 to 1.60) 4.90 (1.55 to 7.55)
 Positive (n = 70; 26, 44)a 2.71 ± 2.41 2.27 ± 1.76 2.97 ± 2.71
2.10 (1.30 to 3.50) 2.00 (1.00 to 3.40) 2.15 (1.40 to 4.10)
P value 0.157 0.089 0.064
HER2 (n = 91; 30, 61)a
 Negative (n = 74; 28, 46)a 3.13 ± 3.51 2.03 ± 1.64 3.80 ± 4.14
2.10 (1.20 to 3.70) 1.75 (1.00 to 3.05) 2.15 (1.30 to 5.80)
 Positive (n = 17; 2, 15)a 4.59 ± 4.16 2.65 ± 3.75 4.85 ± 4.26
3.50 (1.80 to 6.90) 2.65 (0.00 to 5.30) 3.50 (1.80 to 7.30)
P value 0.113 0.900 0.230
EGRF (n = 98; 27, 71)a
 Negative (n = 82; 25, 57)a 2.85 ± 2.86 1.90 ± 1.44 3.26 ± 3.22
2.05 (1.20 to 3.50) 1.80 (1.00 to 2.90) 2.10 (1.30 to 4.80)
 Positive (n =16; 2, 14)a 6.39 ± 5.45 2.65 ± 3.75 6.92 ± 5.55
5.55 (2.40 to 7.25) 2.65 (0.00 to 5.30) 5.95 (2.60 to 7.30)
P value 0.006 0.815 0.013
Ki-67 (n = 99; 27, 72)a
 Negative (n = 57; 22, 35)a 1.90 ± 1.87 1.45 ± 1.22 2.19 ± 2.15
1.60 (1.00 to 2.30) 1.65 (0.00 to 2.30) 1.60 (1.10 to 2.30)
 Positive (n = 42; 5, 37)a 5.41 ± 4.40 4.18 ± 0.88 5.58 ± 4.66
4.75 (2.30 to 7.30) 4.30 (3.40 to 4.70) 5.30 (2.20 to 7.30)
P value < 0.001 0.002 < 0.001
  1. a(n = number of total cases; number of ILC, number of IDC).
  2. EGRF, epidermal growth factor receptor; ER, estrogen receptor; HER2, human epidermal growth factor receptor 2; IDC, invasive ductal carcinoma; ILC, invasive lobular carcinoma; PR, progesterone receptor.