Adult classical glioblastoma with a BRAF V600E mutation

Table 1 Result of next-generation sequencing analysis of glioblastoma

Case	Age	Gender	Type	Gene	ID	Depth	Codon	Amino acid
1	39	M	Primary	FANCA	rs2239359	264	Ggc/Agc	G501S
1	39	M	Primary	STK11	rs59912467	157	ttC/ttG	F354L
2	49	M	Primary	PDGFRA		458	cCg/cGg	p553R
				BRAF	rs121913227	311	gTg/gAg	V600E
				FANCA	rs2239359	1,141	Ggc/Agc	G501S
Recurrence				PDGFRA		458	cCg/cGg	p553R
				BRAF	rs121913227	311	gTg/gAg	V600E
				FANCA	rs2239359	1,141	Ggc/Agc	G501S
3	60	M	Primary	VHL	rs369018004	8,156	Ctg/Gtg	L129V
3	60	M	Primary	FANCA	rs2239359	14,888	Ggc/Agc	G501S
4	42	F	Secondary	FANCA	rs2239359	9,366	Ggc/Agc	G501S
5	55	M	Secondary	IDH1	rs121913500	4,571	cGt/cAt	R132H
				ATM		14,928	Ggt/Agt	G2695S
				FANCA	rs2239359	18,284	Ggc/Agc	G501S
6	79	M	Primary	FANCA	rs2239359	18,284	Ggc/Agc	G501S
7	80	M	Primary	FANCA	rs2239359	3,313	Ggc/Agc	G501S
7	80	M	Primary	STK11	rs59912467	2,723	ttC/ttG	F354L
8	80	M	Primary	FANCA	rs2239359	18,161	Ggc/Agc	G501S
9	58	M	Primary	FANCA	rs2239359	18,161	Ggc/Agc	G501S
9	58	M	Primary	STK11	rs59912467	2,723	ttC/ttG	F354L
10	62	M	Primary	FANCA	rs2239359	513	Ggc/Agc	G501S
11	66	M	Primary	FANCA	rs2239359	8,387	Ggc/Agc	G501S
12	63	F	Primary	PDGFRA	rs2228230	2,959	gtC/gtT	V824
12	63	F	Primary	FANCA	rs2239359	7,658	Ggc/Agc	G501S
13	62	M	Primary	FANCA	rs2239359	8,036	Ggc/Agc	G501S

ISSN: 1477-7819