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Table 2 Efficacy of radiofrequency ablation versus percutaneous ethanol injection for treatment of hepatocellular carcinoma

From: Radiofrequency ablation versus percutaneous ethanol injection for hepatocellular carcinoma: a meta-analysis of randomized controlled trials

First author, year Treatment ( n ) Complete response (%) Overall survival (%) Local recurrence (%)
1-year 2-year 3-year 4-year 5-year 1-year 2-year 3-year 4-year 5-year
Lencioni, 2003 RFA (52) 91.0 100.0 98.0 NA NA NA 2 4 21+ NA NA
  PEI (50) 82.0 96.0 88.0 NA NA NA 17.0 38.0 59.0+ NA NA
Lin, 2004 RFA (52) 96.0 90.0 82.0 74.0 NA NA 12.0 18.0 18.0 NA NA
  PEI (52) 88.0 85.0 61.0 50.0 NA NA 23.0 45.0 45.0 NA NA
Lin, 2005 RFA (62) 96.1 93.0 81.0 74.0 NA NA 10.0 14.0 14.0 NA NA
  PEI (62) 88.1 88.0 66.0 51.0 NA NA 16.0 34.0 34.0 NA NA
Shiina, 2005 RFA (118) 100.0 96.0+ 91.0+ 81.0+ 74.0 NA 1.0+ 1.7+ 1.7+ 1.7+ NA
  PEI (114) 100.0 93.0+ 81.0+ 66.0+ 57.0 NA 9.0+ 11.0+ 11.0+ 11.0+ NA
Brunello, 2008 RFA (70) 95.7 94.0+ 77.0+ 59.0+ 44.0+ NA NA NA NA NA NA
  PEI (69) 65.6 87.0+ 74.0+ 56.0+ 42.0+ NA NA NA NA NA NA
Giorgio, 2011 RFA (128) 100.0 95.0 90.0 83.0 73.0 70.0 4.1 5.7 7.8 8.9 11.7
  PEI (143) 100.0 95.0 83.0 78.0 70.0 68.0 5.2 6.7 9.4 11.5 12.8
Wang, 2011 RFA (49) 93.8 95.9 91.8 NA NA NA NA NA NA NA NA
  PEI (49) 77.5 85.7 77.5 NA NA NA NA NA NA NA NA
Azab, 2011 RFA (30) 85.0 90.0 NA NA NA NA NA NA NA NA NA
  PEI (30) 75.0 83.3 NA NA NA NA NA NA NA NA NA
  1. NA, not available; PEI, percutaneous ethanol injection; RFA, radiofrequency ablation.
  2. +, data extracted from survival curves.