Figure 4
From: sCLU regulates cisplatin chemosensitivity of lung cancer cells in vivo
Expression of clusterin, pERK1/2 and pAKT in A549 tumor tissue from the mice. A549, A549/sCLU, and A549/pCDNA3.1 cells were injected subcutaneously into the right flank of nude mice. Three weeks later, DDP (4 mg/kg body/wt.,i.p) was administered i.v. once every 3 days. The treatments lasted for 15 days. Protein expression in the xenograft tumor was visualized with the indicated antibodies.