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Table 3 Management, resection margin, and recurrence status after hepatectomy

From: Clinical features and prognosis in hepatectomy for colorectal cancer with centrally located liver metastasis

  Centrally located Peripherally located P values
( n = 24) ( n = 135)
Neoadjuvant chemotherapy 4 (16.7%) 11 (8.1%) 0.247
 Effective (stable, partial/complete response 0 (0.0%) 4 (36.4%) 0.159
 Progression 4 (100%) 7 (63.6%)  
Anatomic resectiona 7 (29.2%) 25 (18.5%) 0.269
Resection margin (mm)
 Involved 10 (41.7%) 20 (14.8%) 0.003
 <10 mm 13 (54.2%) 85 (63.0%)  
 ≥10 mm 1 (4.2%) 30 (22.2%)  
Recurrence after hepatectomy 22 (91.7%) 100 (74.1%) 0.045
 Confined in the liver, lung, or both 7 (31.8%) 31 (31.0%) 1.000
 Recurrence in other distant organ(s) 15 (68.2%) 69 (69.0%)  
Early recurrenceb 9 (37.5%) 24 (17.8%) 0.032
Repeated hepatectomy 1 (4.2%) 13 (9.6%) 0.696
  1. aAnatomic resection includes left or right lobectomy, extended left/right lobectomy, or lateral segmetectomy; combination with other hepatectomy methods is excluded; bEarly recurrence: less than 4 months after the hepatectomy for the first liver metastasis.