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Table 1 Specific classification of MRI features

From: Peritumoral edema shown by MRI predicts poor clinical outcome in glioblastoma

Imaging features

Classification criterion

Edema extent

 

 Minor

Peritumoral edema extending <1 cm from tumor margin

 Major

Peritumoral edema extending ≥1 cm from tumor margin

Edema shape

 

 Roundish

The shape of edema is similar to round and is not radial

 Irregular

The shape of edema tends to irregular, such as finger-like or radial shape

Necrosis

 

 No

No necrosis within tumor

 Yes

A region had high signal on T2-W images, but low signal on T1-W images, and had an irregular enhancing border on contrast-enhanced images

Cyst

 

 No

No cyst in tumor

 Yes

A rounded region which was very low T1-W signal and very high T2-W signal matching cerebrospinal fluid signal, and had a thin, smooth, regular, and slightly enhancing or non-enhancing wall

Enhancement

 

 No obvious

Enhancement signal is less than the signal of fat

 Obvious

Enhancement signal is similar to that of fat

Tumor crosses midline

 

 No

Tumor is limited to unilateral cerebral hemisphere

 Yes

Tumor crosses the brain midline and extends into the other side of cerebral hemisphere

Edema crosses midline

 

 No

Peritumoral edema extent is limited to unilateral cerebral hemisphere

 Yes

Peritumoral edema extent crosses the brain midline and is not confined to unilateral cerebral hemisphere

Size (cm)

 

 <5

The maximum diameter of tumor is less than 5 cm

 ≥5

The maximum diameter of tumor is equal to or more than 5 cm