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Table 1 Specific classification of MRI features

From: Peritumoral edema shown by MRI predicts poor clinical outcome in glioblastoma

Imaging features Classification criterion
Edema extent  
 Minor Peritumoral edema extending <1 cm from tumor margin
 Major Peritumoral edema extending ≥1 cm from tumor margin
Edema shape  
 Roundish The shape of edema is similar to round and is not radial
 Irregular The shape of edema tends to irregular, such as finger-like or radial shape
Necrosis  
 No No necrosis within tumor
 Yes A region had high signal on T2-W images, but low signal on T1-W images, and had an irregular enhancing border on contrast-enhanced images
Cyst  
 No No cyst in tumor
 Yes A rounded region which was very low T1-W signal and very high T2-W signal matching cerebrospinal fluid signal, and had a thin, smooth, regular, and slightly enhancing or non-enhancing wall
Enhancement  
 No obvious Enhancement signal is less than the signal of fat
 Obvious Enhancement signal is similar to that of fat
Tumor crosses midline  
 No Tumor is limited to unilateral cerebral hemisphere
 Yes Tumor crosses the brain midline and extends into the other side of cerebral hemisphere
Edema crosses midline  
 No Peritumoral edema extent is limited to unilateral cerebral hemisphere
 Yes Peritumoral edema extent crosses the brain midline and is not confined to unilateral cerebral hemisphere
Size (cm)  
 <5 The maximum diameter of tumor is less than 5 cm
 ≥5 The maximum diameter of tumor is equal to or more than 5 cm