From: Peritumoral edema shown by MRI predicts poor clinical outcome in glioblastoma
Imaging features | Classification criterion |
---|---|
Edema extent | Â |
 Minor | Peritumoral edema extending <1 cm from tumor margin |
 Major | Peritumoral edema extending ≥1 cm from tumor margin |
Edema shape | Â |
 Roundish | The shape of edema is similar to round and is not radial |
 Irregular | The shape of edema tends to irregular, such as finger-like or radial shape |
Necrosis | Â |
 No | No necrosis within tumor |
 Yes | A region had high signal on T2-W images, but low signal on T1-W images, and had an irregular enhancing border on contrast-enhanced images |
Cyst | Â |
 No | No cyst in tumor |
 Yes | A rounded region which was very low T1-W signal and very high T2-W signal matching cerebrospinal fluid signal, and had a thin, smooth, regular, and slightly enhancing or non-enhancing wall |
Enhancement | Â |
 No obvious | Enhancement signal is less than the signal of fat |
 Obvious | Enhancement signal is similar to that of fat |
Tumor crosses midline | Â |
 No | Tumor is limited to unilateral cerebral hemisphere |
 Yes | Tumor crosses the brain midline and extends into the other side of cerebral hemisphere |
Edema crosses midline | Â |
 No | Peritumoral edema extent is limited to unilateral cerebral hemisphere |
 Yes | Peritumoral edema extent crosses the brain midline and is not confined to unilateral cerebral hemisphere |
Size (cm) | Â |
 <5 | The maximum diameter of tumor is less than 5 cm |
 ≥5 | The maximum diameter of tumor is equal to or more than 5 cm |