Clinicopathological significance of CD133 and CD44 expression in infiltrating ductal carcinoma and their relationship to angiogenesis

Table 1 Values of CD133, CD44, and CD82 expression and MVD and clinicopathological characteristics in IDC

Variable	CD133		P value	CD44		P value	CD82		P value	MVD mean	F	P value
Variable	Negative	Positive	P value	Negative	Positive	P value	Negative	Positive	P value	MVD mean	F	P value
Age (years)
<45	73	73	0.652	70	76	0.559	88	58	0.423	22.1 ± 8.0	12.297	0.001
≥45	94	85	0.652	80	99	0.559	100	79	0.423	19.2 ± 5.7	12.297	0.001
Site
Left	90	80	0.557	75	95	0.441	101	69	0.549	20.6 ± 7.1	0.038	0.846
Right	77	78	0.557	75	80	0.441	87	68	0.549	20.4 ± 6.8	0.038	0.846
Diameter
<2.0 cm	54	37	0.197	47	44	0.272	43	48	0.033	21.3 ± 6.5	0.701	0.497
2.0 to 5.0 cm	95	103		90	106		120	78		20.4 ± 6.7
≥5.0 cm	18	18		13	23		25	11		19.6 ± 9.1
Grade of tumor
1	49	27	0.033	45	31	0.019	33	43	0.013	19.8 ± 6.6	3.218	0.041
2	76	83		71	88		101	58		21.2 ± 6.6
3	42	48		34	56		54	36		20.0 ± 7.9
Lymph node metastasis
No	102	53	<0.001	83	72	0.011	74	81	<0.001	18.7 ± 5.6	20.633	<0.001
Yes	65	105	<0.001	67	103	0.011	114	56	<0.001	22.2 ± 7.7	20.633	<0.001
TNM stage
I + II	104	73	0.004	91	86	0.038	93	84	0.034	18.8 ± 6.1	57.775	<0.001
III + IV	63	85	0.004	59	89	0.038	95	53	0.034	22.6 ± 7.3	57.775	<0.001
ER expression
Negative	57	70	0.060	46	81	0.004	79	48	0.203	21.8 ± 6.9	13.109	<0.001
Positive	110	88	0.060	104	94	0.004	109	89	0.203	19.8 ± 6.9	13.109	<0.001
PR expression
Negative	67	80	0.057	69	78	0.796	78	69	0.112	20.7 ± 7.3	0.195	0.659
Positive	100	78	0.057	81	97	0.796	110	68	0.112	20.4 ± 6.7	0.195	0.659
Her-2 expression
Negative	110	85	0.026	100	95	0.023	102	93	0.013	19.7 ± 6.9	5.397	0.021
Positive	57	73	0.026	50	80	0.023	86	44	0.013	21.9 ± 6.9	5.397	0.021

ISSN: 1477-7819