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Table 7 Multivariate analysis of risk factors for observed survival

From: Correlation between mutational status and survival and second cancer risk assessment in patients with gastrointestinal stromal tumors: a population-based study

Variable

HR

p value

Age (>65 vs 0 to 64 years old)

2.22 (1.11 to 4.41)

0.02

Sex (men vs women)

1.78 (0.96 to 3.26)

0.06

Type of mutation

  

KIT 09 vs KIT 11

1.46 (0.44 to 4.79)

0.53

PDGRF vs KIT 11

1.07 (0.4 to 2.87)

0.90

WT vs KIT 11

1.21 (0.56 to 2.57)

0.63

All other vs KIT 11

0.83 (0.44 to 1.58)

0.58

Fletcher’s risk groups

  

IR vs LR

1.58 (0.65 to 3.88)

0.32

HR vs LR

2.27 (0.96 to 5.37)

0.06

Met vs LR

11.49 (2.9 to 45.54)

<0.001

Site

  

C17 vs C16

1.08 (0.57 to 2.05)

0.82

All other vs C16

1.23 (0.33 to 4.58)

0.76

  1. Data in italics show significance.
  2. HR, hazard ratio; LR, low risk (includes very low risk); IR, intermediate risk; HR, high risk; Met, diagnosed in metastatic disease; C16, stomach; C17, small intestine.