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Table 3 Type of mutation in the 108 GIST cases analyzed

From: Correlation between mutational status and survival and second cancer risk assessment in patients with gastrointestinal stromal tumors: a population-based study

Exon mutated

Type of mutation

Number of cases

Exon 11 gene c-KIT

V559D

8

W557_K558del

7

V560D

4

L576P

3

R558_L589insDHKWEFPRN

2

Y570_P577del

2

H580_K581insIDPTQLPY

2

V559A

2

V555_V559del

2

V560_E561del

2

T574_P577del

2

V557_K561del

1

W557_E561del

1

W557_E562del

1

T574_Q575insDP

1

V559G

1

Q556_V559 > H

1

Q556_T574del

1

P585S

1

P577S

1

N567_Q575del

1

N567_P577 > Y

1

N566Y

1

V560del

1

K558R

1

K558_V560del

1

K558_G565del

1

K550_P551insK

1

W557_V559del

1

E554_K558del

1

D579del

1

557-558 del

1

I563_P577del

1

Exon 9 gene c-KIT

Y503_F504insAY

8

Exon 18 gene PDGFR-α

D842V

11

D842_H845del

1

I843_D846del

1

Exon 12 gene PDGFR-α

D591Y

1

W559_V561del

1

Wild type

 

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