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Table 2 Univariate and multivariate analyses related to disease-free survival in 97 colorectal cancer patients

From: Prognostic value of HLA class I expression in patients with colorectal cancer

Variables

Univariate

Multivariate

Hazard ratio

P value

Hazard ratio

P value

Age

0.98 (0.94–1.02)

0.38

  

Gender (F)

1.42 (0.50–4.04)

0.51

  

Tumor location (colon vs rectum)

4.23 (1.49–12.01)

0.01

4.11 (1.42–11.91)

0.009

Tumor size (5 cm)

0.64 (0.24–1.73)

0.38

  

Tumor invasion (SI)

0.52 (0.12–2.28)

0.39

  

Differentiation (por or muc)

1.50 (0.20–11.35)

0.70

  

Lymphatic invasion (ly0, 1 vs ly2, 3)

1.10 (0.25–4.83)

0.90

  

Venous invasion (v0, 1 vs v2, 3)

3.10 (1.00–9.56)

0.05

3.85 (1.15–12.92)

0.03

Budding

0.52 (0.19–1.41)

0.20

  

Number of lymph nodes analyzed (<12)

1.32 (0.51–3.43)

0.57

  

HLA expression level (dull or negative)

3.86 (1.26–11.85)

0.02

5.36 (1.68–17.11)

0.005

Adjuvant chemotherapy (no)

0.82 (0.30–2.22)

0.70