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Figure 6 | World Journal of Surgical Oncology

Figure 6

From: pERK1/2 silencing sensitizes pancreatic cancer BXPC-3 cell to gemcitabine-induced apoptosis via regulating Bax and Bcl-2 expression

Figure 6

Modulation of sensitivity to gemcitabine by ERK1/2-Bax signal. Cells were pre-cotreated with PD98059 and Bax siRNA for 24 h and then treated with 0–25 uM gemcitabine for 72 h. (A) Western blot assay for Bax expression in BXPC-3 cells; (B) cell apoptosis was determined using the ELISA; and (C) cell apoptosis was determined using the TUNEL assay. *P < 0.05.

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World Journal of Surgical Oncology

ISSN: 1477-7819

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