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Table 1 Clinical and histopathological characteristics of patients

From: Clinical and oncological outcomes in Chinese patients with renal cell carcinoma and venous tumor thrombus extension: single-center experience

Variables

Total

Renal vein thrombus

IVC thrombus

P value

N (%)

86

53(61.6)

33(38.4)

 

Age, year

57.7 ± 11.3

57.1 ± 11.5

58.7 ± 11.2

0.535

Gender (%)

    

  Male

58(67.4)

35(66)

23(69.7)

0.725

  Female

28(32.6)

18(34)

10(30.3)

 

Laterality (%)

    

  Left

39(45.3)

27(50.9)

12(36.4)

0.187

  Right

47(54.7)

26(49.1)

21(63.6)

 

Clinical symptom (%)

    

  Yes

47(54.7)

26(49.1)

21(63.6)

0.187

  No

39(45.3)

27(50.9)

12(36.4)

 

Tumor size, cm

8.2 ± 2.4

8.1 ± 2.2

8.3 ± 2.5

0.731

ECOG-PS

0.8 ± 0.8

0.6 ± 0.8

1.2 ± 0.7

0.04

Histological type (%)

    

  Clear cell

67(77.9)

43(81.1)

24(72.7)

0.361

  Others

19(22.1)

10(18.9)

9(27.3)

 

Tumor grade (%)

    

  G1

6(7.0)

6(11.3)

0(0)

 

  G2

38(44.2)

24(45.3)

14(42.4)

0.156

  G3

33(38.4)

19(35.8)

14(42.4)

 

  G4

9(10.5)

4(7.5)

5(15.2)

 

T stage (%)

    

  T3a

50(58.1)

49(92.5)

0(0)

 

  T3b

17(19.8)

0(0)

18(54.5)

0.000

  T3c

10(11.6)

0(0)

10(30.3)

 

  T4

9(10.5)

4(7.5)

5(15.2)

 

N stage (%)

    

  N0 or Nx

70(81.4)

45(84.9)

25(75.8)

0.289

  N1

16(18.6)

8(15.1)

8(24.2)

 

M stage (%)

    

  M0

75(87.2)

50(94.3)

25(75.8)

0.029

  M1

11(12.8)

3(5.7)

8(24.2)

 

Perinephric fat invasion (%)

    

  Yes

31(36.0)

11(20.8)

20(60.6)

0.000

  No

55(64.0)

42(79.2)

13(39.4)

 

Renal pelvis invasion (%)

    

  Yes

10(11.6)

5(9.4)

5(15.2)

0.647

  No

76(88.4)

48(90.6)

28(84.8)

 

Thrombus level (%)

    

  Renal vein

53(61.6)

53(100)

0(0)

 

  I

16(18.6)

0(0)

16(48.5)

0.000

  II

11(12.8)

0(0)

11(33.3)

 

  III

6(7.0)

0(0)

6(18.2)

 

Invasion of IVC wall (%)

    

  Yes

12(14.0)

0(0)

12(36.4)

0.000

  No

74(86.0)

53(100)

21(63.6)

 

Neoadjuvant-molecular-targeted therapy (%)

    

  Yes

2(2.3)

0(0)

2(6.1)

0.144

  No

84(97.7)

53(100)

31(93.9)