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Table 4 Haplotype and diplotype of ACLY gene and CRC survival

From: Functional polymorphisms of ATP citrate lyase gene predicts clinical outcome of patients with advanced colorectal cancer

Group

Frequency (%)

Death

Recurrence

HR a (95% CI)

P value

HR a (95% CI)

P value

Haplotype

     

  T-T

82.10

Ref.

 

Ref.

 

  T-G

9.90

0.92(0.66–1.29)

0.64

0.87(0.64–1.18)

0.36

  G-G

8.00

0.86(0.59–1.26)

0.44

0.84(0.59–1.20)

0.34

Diplotype

     

  T_T-T_T

66.60

Ref.

 

Ref.

 

  T_T-T_G

15.80

0.90(0.61–1.33)

0.58

0.84(0.58–1.21)

0.34

  T_G-T_G

14.90

0.80(0.53–1.22)

0.30

0.76(0.52–1.12)

0.16

  1. Significant P values (<0.05) are in italics.
  2. Abbreviations: CI, confidence interval; HR, hazard ratio; Ref., reference.
  3. aAdjusted by gender, age, hospital site, tumor position, TNM stage, tumor differentiation, and treatment after surgery where appropriate.