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Figure 4 | World Journal of Surgical Oncology

Figure 4

From: CCR9-CCL25 interactions promote cisplatin resistance in breast cancer cell through Akt activation in a PI3K-dependent and FAK-independent fashion

Figure 4

GSK-3β and FKHR phosphorylation following CCL25 treatment. MDA-MB-231 cells were tested for their ability to phosphorylate GSK-3β and FKHR following treatment with CCL25, cisplatin and specific-kinase inhibitors (wortmannin and PF-573, 228). In situ total and active (phosphorylated) GSK-3β and FKHR levels were quantified by Fast Activated Cell-based ELISA (FACE) assay before (0 minutes) or after (5 or 10 minutes) CCL25 stimulation in the presence of cisplatin and kinase inhibitors.

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