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Table 4 Grade 3/4 toxicity of chemotherapy according to NCI-CTC grade

From: Video-assisted thoracoscopic surgery is more favorable than thoracotomy for administration of adjuvant chemotherapy after lobectomy for non-small cell lung cancer

 

VATS

n = 54

Thoracotomy

n = 56

p value

Hematologic,no. (%)

9(16.7)

18(33.3)

0.046*

   Leukopenia

5 (9.3)

9 (16.1)

0.284

   Neutropenia

7(13.0)

14 (25.0)

0.108

   Anemia

1(1.9)

0(0.0)

0.491

   Thrombocytopenia

1(1.9)

0(0.0)

0.491

Non-hematologic, no. (%)

6 (11.1)

15(26.8)

0.037*

   Nausea

6 (11.1)

14 (25.0)

0.059

   Vomiting

3 (5.6)

5(8.9)

0.716

   Fatigue/asthenia

1 (1.9)

3 (5.4)

0.618

   Diarrhea/constipation

1 (1.9)

2 (3.6)

1.000

   Neuropathy: sensory

1 (1.9)

1 (1.8)

1.000

   Phlebitis

0 (0.0)

0 (0.0)

1.000

   Infection

0 (0.0)

0 (0.0)

1.000