Figure 1

Segment 7 hepatic metastasis from colorectal cancer: (a) Preoperative patient diagnostic PET/CT scan demonstrating an ¹⁸F-FDG-avid lesion in the liver (red circle). (b) Postoperative patient diagnostic PET/CT demonstrating complete removal of the ¹⁸F-FDG-avid lesion (red circle). (c) Digital photo of the WSRS (i.e., segment 7 liver resection specimen), visualizing the hepatic metastasis (red oval). (d) Clinical PET/CT specimen image and (e) micro PET/CT specimen image of the WSRS, demonstrating the ¹⁸F-FDG-avid lesion (red oval). (f) Digital photo depicting the first phase of the pathologic processing that produced the RDT, which consists of a single 0.5 cm slice through the hepatic metastasis. (g) Clinical PET/CT specimen image and (h) micro PET/CT specimen image of the RDT, demonstrating the ¹⁸F-FDG-avid lesion that corresponds to the hepatic metastasis. (i) Digital photo after sectioning of the RDT into five pieces of tissue, designated as SRDT, with two pieces containing visible tumor. (j) Clinical PET/CT specimen image and (k) micro PET/CT image of the SRDT, demonstrating ¹⁸F-FDG avidity in the two pieces that corresponds to the hepatic metastasis. (l) H&E stained, whole-mount slide (0.4× magnification) of the specific SRDT piece that is highlighted in the red rectangle in (i), (j), and (k), demonstrating histologic confirmation of a colorectal cancer hepatic metastasis and the corresponding location of tumor within this specific SRDT piece. Each division of the hatched line in (c), (f), and (i) represents 1 cm.