Figure 1From: Low back pain as the presenting sign in a patient with primary extradural melanoma of the thoracic spine - A metastatic disease 17 Years after complete surgical resectionHistopathological evaluation. Hematoxylin and eosin histologic analysis revealed a highly cellular malignant tumour with prominent nucleoli (image A 100×, images B and C 200×, image D 400×). Immunohistochemical study shows that the tumour cells stained diffusely positive for Melan-A and HMB-45, consistent with the diagnosis of melanoma (images E 200×, image F 400×).Back to article page