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Table 2 Analyses of treatment-related variables associated with recurrence/progression in MOGCTs

From: Residual tumor after the salvage surgery is the major risk factors for primary treatment failure in malignant ovarian germ cell tumors: A retrospective study of single institution

Variables

No. Patients (%)

Recurrence No

(Rate, %)

P value

Treatment modalities

   

   Surgery only

8(14.0)

1(1.8)

0.4342

   Surgery + chemotherapy

49(86.0)

5(8.8)

 

Operation methods

   

   Fertility sparing

42(73.7)

1(1.8)

0.0006

Cystectomy without staging op.

1(1.8)

0(0.0)

 

USO without staging op.

20(35.1)

0(0.0)

 

USO with staging op.

21(36.8)

1(1.8)

 

   Non-fertility sparing

15(26.3)

5(8.8)

 

Hysterectomy + BSO without staging op.

5(8.8)

0(0.0)

 

Hysterectomy + BSO with staging op.

10(17.5)

5(8.8)

 

Chemotherapy regimens (n = 49)

   

   BEP

9(18.4)

1(2.0)

0.9008

   EP

28(57.1)

3(6.1)

 

   VBP

2(4.1)

0(0.0)

 

   Others

10(20.4)

10(20.4)

 

Residual lesions

   

   None

47(82.5)

1(1.8)

< 0.0001

   ≤ 1 cm

8(14.0)

3(5.3)

 

   > 1 cm

2(3.5)

2(3.5)

 
  1. USO, unilateral salpingo-oophorectomy; BSO, bilateral salpingo-oophorectomy; BEP, bleomycin, etoposide, and cisplatin; EP, etoposide and cisplatin; VBP, vinblastine, bleomycin, and cisplatin.