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Table 2 Cox proportional hazard analysis of risk factors for 5-year overall and disease-free survival

From: Evaluation of the new AJCC staging system for resectable hepatocellular carcinoma

  Overall survival Disease-free survival
  HR 95% C.I. p -value HR 95% C.I. p -value
Vascular invasion 1.39 1.14-1.70 < 0.01 1.15 0.94-1.40 0.18
Satellite lesions 1.23 1.03-1.47 0.03 1.17 0.97-1.40 0.10
Rupture 1.53 0.98-2.40 0.06 1.21 0.76-1.91 043
Cirrhosis 0.90 0.66-1.21 0.47 0.96 0.70-1.30 0.80
Encapsulation 0.67 0.49-0.91 0.01 0.73 0.53-0.99 0.04
Grade (III, IV vs. I, II) 1.02 0.98-1.14 0.71 1.05 0.94-1.17 0.42
Albumin 0.97 0.64-1.47 0.88 0.75 0.49-1.14 0.17
AST (> 68 vs. ≤ 68 U/L) 1.84 1.30-2.61 < 0.01 1.65 1.14-2.40 0.01
Bil (> 1.3 ≤ vs. ( 1.3 mg/dL) 1.40 0.89-2.02 0.16 0.98 0.64-1.14 0.91
AFP (200 ng/mL) 1.44 1.05-1.98 0.02 1.28 0.94-1.75 0.123
Blood loss (> 0.5 L) 1.85 1.36-2.53 < 0.01 1.43 1.05-1.94 0.03
Margin involved 0.84 0.63-1.12 0.29 0.78 0.59-1.04 0.09
  1. Grade: Edmonson and Steiner; AST, aspartate aminotransferase; Bil, total bilirubin; AFP, α-fetoprotein ICG, indocyanine green