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Table 2 Cox proportional hazard analysis of risk factors for 5-year overall and disease-free survival

From: Evaluation of the new AJCC staging system for resectable hepatocellular carcinoma

 

Overall survival

Disease-free survival

 

HR

95% C.I.

p -value

HR

95% C.I.

p -value

Vascular invasion

1.39

1.14-1.70

< 0.01

1.15

0.94-1.40

0.18

Satellite lesions

1.23

1.03-1.47

0.03

1.17

0.97-1.40

0.10

Rupture

1.53

0.98-2.40

0.06

1.21

0.76-1.91

043

Cirrhosis

0.90

0.66-1.21

0.47

0.96

0.70-1.30

0.80

Encapsulation

0.67

0.49-0.91

0.01

0.73

0.53-0.99

0.04

Grade (III, IV vs. I, II)

1.02

0.98-1.14

0.71

1.05

0.94-1.17

0.42

Albumin

0.97

0.64-1.47

0.88

0.75

0.49-1.14

0.17

AST (> 68 vs. ≤ 68 U/L)

1.84

1.30-2.61

< 0.01

1.65

1.14-2.40

0.01

Bil (> 1.3 ≤ vs. ( 1.3 mg/dL)

1.40

0.89-2.02

0.16

0.98

0.64-1.14

0.91

AFP (200 ng/mL)

1.44

1.05-1.98

0.02

1.28

0.94-1.75

0.123

Blood loss (> 0.5 L)

1.85

1.36-2.53

< 0.01

1.43

1.05-1.94

0.03

Margin involved

0.84

0.63-1.12

0.29

0.78

0.59-1.04

0.09

  1. Grade: Edmonson and Steiner; AST, aspartate aminotransferase; Bil, total bilirubin; AFP, α-fetoprotein ICG, indocyanine green
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World Journal of Surgical Oncology

ISSN: 1477-7819

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