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Table 2 Summary of pooled risk ratios of bladder cancer for fish consumer by study design, geographical region, and exposure assessment

From: The association of fish consumption with bladder cancer risk: A meta-analysis

Subgroup

Number of studies

Pooled RR

(95% CI)

Q-test for heterogeneity

   

P value

I2 score

Study design

Cohort studies

5

0.84 (0.42, 1.26)

0.023

64.8%

Case-control studies

9

0.87 (0.54, 1.21)

< 0.001

89.7%

Hospital-based case-control studies

6

0.88 (0.40, 1.36)

< 0.001

92.5%

Population-based case-control studies

3

0.83 (0.63, 1.03)

0.586

0

Geographical region

Europe

7

0.95 (0.49, 1.42)

< 0.001

91.9%

US/Canada

3

0.80 (0.58, 1.02)

0.891

0

Japan

3

0.76 (0.25, 1.27)

0.019

74.7%

Exposure assessment

Interview

6

0.88 (0.40, 1.36)

< 0.001

92.5%

Mailed questionnaire

7

0.84 (0.58, 1.09)

0.025

58.5%

Case sample size

Large

7

0.99 (0.82, 1.17)

0.215

28.0%

Small

7

0.68 (0.34, 1.02)

< 0.001

81.4%