Figure 2

Tumor cells are arranged in a trabecular and solid pattern. 2a: Tumor cells are arranged in a trabecular and solid pattern and containing bile plugs (HE×100), 2b: Tumor cells have abundant eosinophilic cytoplasm, enlarged nuclei and prominent nucleoli (HE×400). 2c: Foci of well-differentiated gallbladder adenocarcinoma (HE×400.), 2d: Foci of high-grade dysplasia were observed in the gallbladder epithelium adjacent to the tumor (HE×200)