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Table 2 Disease distribution and Clinical results

From: Clinical relevance of "withdrawal therapy" as a form of hormonal manipulation for breast cancer

Patients (n)

Disease type

CB = n (%)

DoCB in months

DoT in months

All (n = 17)

14 MBC

3 LAPC

10 (58.8%); 1PR,9SD

(8 MBC & 2 LAPC)

10+ (7-27)

9+ (1-27)

Tamoxifen (n = 10)

9 MBC

1 LAPC

6 (60%); 1 PR, 5 SD

(6 MBC)

10.5+ (7-27)

8.5+ (1-27)

Rest (n = 7)

1M,1F,4E,1L

5 MBC

2 LAPC

4 (57.1%); 4 SD

(2 MBC & 2 LAPC)

9.5+ (9-23)

9+ (2-23)

  1. M = Megestrol acetate; F = Fulvestrant; E = Exemestane; L = Letrozole; MBC = Metastatic Breast Cancer; LAPC = Locally Advanced Primary Breast Cancer; PR = Partial Response; SD = Stable Disease; DoCB = Duration of Treatment in patients with Clinical Benefit; DoT = Duration of Treatment irrespective of response