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Table 3 Univariate analysis of prognostic factors in young patients - Cox Proportional Hazard Model

From: Young patients with colorectal cancer have poor survival in the first twenty months after operation and predictable survival in the medium and long-term: Analysis of survival and prognostic markers

Variable

Factor Division

n

Hazard Ratio

p

Gender

Male

49

1.436

0.4751

 

Female

   

Neoadjuvant therapy

Not given

48

3.012

0.0382

 

Given

   

Duration of symptoms

≤ 3 months

39

0.804

0.7472

 

>3 months

   

CEA level

normal

33

1.508

0.5916

 

elevated

   

Tumour location

Right colon

43

1.021

0.9586

 

Left colon

   
 

Rectum

   

Histology

adenocarcinoma

46

1.237

0.7806

 

mucinous

   

Differentiation (1)

Well

46

1.716

0.2131

 

Moderately

   
 

Poorly

   

Differentiation (2)

Well

46

1.413

0.6510

 

Non-well

   

Differentiation (3)

Poorly

46

0.451

0.1475

 

Non-poorly

   

AJCC stage (1)

I

46

1.835

0.0799

 

II

   
 

III

   
 

IV

   

AJCC stage (2)

I

46

1.257

0.7637

 

I1, 111 and 1V

   

AJCC stage (3)

1 and II

46

2.524

0.1134

 

II,111 and 1V

   

AJCC stage (4)

1,11 and III

46

3.925

0.0367

 

IV

   

Resection Margin

R0

46

3.684

0.0142

 

R1

   

Perineural invasion

-

38

2.591

0.2304

 

+

   

Lymphatic invasion

-

37

2.909

0.1729

 

+

   

Vascular invasion

-

38

2.404

0.1460

 

+

   

Tumor margin

Pushing

13

0.817

0.8691

 

Infiltrating

   

Adjuvant therapy (1)

Given

39

3.350

0.2471

 

Not Given

   

Adjuvant therapy (2)

Chemotherapy

39

0.4174

0.6576