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Table 3 Univariate analysis of prognostic factors in young patients - Cox Proportional Hazard Model

From: Young patients with colorectal cancer have poor survival in the first twenty months after operation and predictable survival in the medium and long-term: Analysis of survival and prognostic markers

Variable Factor Division n Hazard Ratio p
Gender Male 49 1.436 0.4751
  Female    
Neoadjuvant therapy Not given 48 3.012 0.0382
  Given    
Duration of symptoms ≤ 3 months 39 0.804 0.7472
  >3 months    
CEA level normal 33 1.508 0.5916
  elevated    
Tumour location Right colon 43 1.021 0.9586
  Left colon    
  Rectum    
Histology adenocarcinoma 46 1.237 0.7806
  mucinous    
Differentiation (1) Well 46 1.716 0.2131
  Moderately    
  Poorly    
Differentiation (2) Well 46 1.413 0.6510
  Non-well    
Differentiation (3) Poorly 46 0.451 0.1475
  Non-poorly    
AJCC stage (1) I 46 1.835 0.0799
  II    
  III    
  IV    
AJCC stage (2) I 46 1.257 0.7637
  I1, 111 and 1V    
AJCC stage (3) 1 and II 46 2.524 0.1134
  II,111 and 1V    
AJCC stage (4) 1,11 and III 46 3.925 0.0367
  IV    
Resection Margin R0 46 3.684 0.0142
  R1    
Perineural invasion - 38 2.591 0.2304
  +    
Lymphatic invasion - 37 2.909 0.1729
  +    
Vascular invasion - 38 2.404 0.1460
  +    
Tumor margin Pushing 13 0.817 0.8691
  Infiltrating    
Adjuvant therapy (1) Given 39 3.350 0.2471
  Not Given    
Adjuvant therapy (2) Chemotherapy 39 0.4174 0.6576