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Table 2 Comparison of clinical and pathological features in young (n = 53) versus older patients (n = 47) having colorectal cancer

From: Young patients with colorectal cancer have poor survival in the first twenty months after operation and predictable survival in the medium and long-term: Analysis of survival and prognostic markers

Variable

 

<40 years

≥50 years

Gender

Male

26 (51%)

26(45%)

 

Female

27 (49%)

21(55%)

Duration of symptoms*

≤ 3 months

22 (41.5%)

22 (47%)

 

>3 months

31 (58.5%)

25 (53%)

Tumour Location

Right colon (included 2 synchronous lesions in <40 year group)

10 (17.5%)

3 (6%)

 

Left colon (included 2 synchronous lesions in <40 year group)

10 (17.5%)

13(28%)

 

Rectal

37 (65%)

31 (66%)

Histological types

Adenocarcinoma (included 4 synchronous lesions in the young)

48 (84%)

43 (92%)

 

Mucinous

5 (9%)

2 (4%)

 

Signet ring

4 (7.0%)

2 (4%)

Tumor grade

Well

10 (18.9%)

2 (4%)

 

Moderate

33 (62.2%)

43(92%)

 

Poor

10 (18.9%)

2 (4%)

T stage

T0/1

5 (9.2%)

2 (4%)

 

T2

11 (20.4%)

9 (19%)

 

T3

24 (44.4%)

28 (60%)

 

T4

11 (20.4%)

8 (17%)

 

No residual tumor after chemoradiation

3 (5.6%)

Nil

N stage

N0

28 (51.8%)

25(54.3%)

 

N1

13 (24.1%)

8 (17.4%)

 

N2

13 (24.1%)

13 (28.3%)

AJCC staging *

I

7 (14.0%)

6 (12.8%)

 

II

16 (32.0%)

20 (42.6%)

 

III

24 (48.0%)

15 (31.9%)

 

IV

3 (6.0%)

6 (12.8%)

Pre-operative CEA level (ng/ml)

<5.0

17 (51.5%)

16 (34%)

 

>5.0

16 (48.5%)

31(66%)

Resection margin #

R0

40 (80.0%)

35 (74.5%)

 

R1

10 (20.0%)

12 (25.5%)

  1. * Data were not available in one of the older group. # Data were not available in three young patients.