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Table 5 Results of Binary Logistic Regression analysis of CAG (AR2) repeats in relation to covariates (n = 70)

From: Androgen receptor status predicts response to chemotherapy, not risk of breast cancer in Indian women

Variables

 

Unadjusted

Adjusted

 

Distribution of Genotype in Cases

OR (95% C.I.)

P value

OR (95% C.I.)

P Value

 

AR1 (36) (R%, C%)!

AR2 (34) (R%, C%)!

    

Age of onset

      

Late onset (20)

8 (40, 22.2)

22 (44, 64.8)

1.000

0.397

1.000

0.160

Early onset (50)

28 (56, 77.8)

12 (60, 35.2)

0.786 (0.450, 1.373)

 

0.454 (0.151, 1.365)

 

Family History

      

No FH (59)

30 (50.8, 83.3)

29 (49.2, 85.3)

1.000

0.763

1.000

0.523

Having FH (11)

6 (54.5, 16.7)

5 (45.5, 14.7)

0.833 (0.254, 2.731)

 

0.637 (0.160, 2.539)

 

Stages of Disease

      

Initial stages (I + II) (23)

13 (56.5, 36.1)

10 (43.5, 29.4)

1.000

0.884

1.000

0.486

Advance stages (III + IV) (47)

23 (48.9, 63.9)

24 (51.1, 70.6)

1.043 (0.589, 1.849)

 

1.461 (0.503, 4.243)

 

Grade

      

Lower (I + II) (52)

29 (55.8, 80.6)

23 (44.2, 67.6)

1.000

0.350

1.000

0.120

Higher (III) (18)

7 (38.9,19.4)

11 (61.1, 32.4)

1.571 (0.609, 4.054)

 

2.470 (0.781, 7.817)

 

Estrogen receptor status

N= 18

N= 18

1.000

0.530

  

Positive (10)

6 (60, 33.3)

4 (40, 22.2)

0.667 (0.188, 2.362)

   

Negative (26)

12 (46.2, 66.7)

14 (53.8, 77.8)

    

Androgen receptor status

N = 20

N = 26

1.000

   

Positive (16)

8 (50, 40)

8 (50, 30.7)

0.668 (0.196, 2.263)

0.516

  

Negative (30)

12 (40, 60)

18 (60, 69.3)

    
  1. !:(R%: row percentages, C%: column percentages)