Table 3 Characteristics of the included studies
First author | Year | Intrahepatic recurrences rate (%) | Median recurrent Intervals (months) | Resectability rate (%) | No. of repeat hepatectomy | Male/ female | Mean age (years) | Liver cirrhosis (%) | Solitary recurrent HCC (%) | Maxium tumor size (<3 cm) (%) |
|---|---|---|---|---|---|---|---|---|---|---|
Lange [8] | 1989 | -- | 9 | -- | 11 | 9/2 | 45 | 36 | 54.5 | 27 |
Nakajima [9] | 1993 | 36.8 | -- | 28.5 | 14 | -- | -- | 50 | 64.2 | 64.2 |
Matsuda [10] | 1993 | 40 | 18 | 44 | 16 | 13/3 | 63.3 | 100 | -- | -- |
Wu [11] | 1993 | -- | -- | -- | 72 | 66/6 | 45.8 | 63.9 | -- | -- |
Zhou [12] | 1993 | 48.2 | -- | 35 | 65 | -- | -- | -- | -- | -- |
Kakazu [13] | 1993 | 78 | 26* | 11 | 24 | 19/5 | 59.5 | -- | 62.5 | -- |
Suenaga [14] | 1994 | 61.2 | 33.3* | 24.3 | 18 | 13/5 | 56.9 | 88.8 | 72.2 | 67 |
Lee [15] | 1995 | 40.8 | 18 | 31.2 | 25 | 17/8 | 55.8 | 76 | 60 | 32 |
Nagasue [16] | 1996 | -- | 21* | 30 | 50 | 36/14 | 59 | 76 | 70 | -- |
Shuto [17] | 1996 | 57 | Â | 16 | 31 | 27/4 | 60 | 94 | 64.5 | -- |
Hu [18] | 1996 | -- | 23 | -- | 59 | 46/13 | 52 | -- | 66.1 | -- |
Shimada [19] | 1998 | -- | -- | -- | 41 | 33/8 | -- | 56 | 65.8 | 70.7 |
Arii [20] | 1998 | -- | -- | 12.6 | 22 | 16/6 | 60 | 68.2 | 63.6 | -- |
Farges [21] | 1998 | 67 | -- | 16.8 | 15 | -- | -- | -- | -- | -- |
Poon [5] | 1999 | 43 | 6 | 10 | 11 | -- | -- | -- | -- | -- |
Nakajima [22] | 2001 | 60.6 | 31 | 21 | 12 | 10/2 | 62.3 | 41.6 | 83.3 | -- |
Sugimachi [23] | 2001 | 63.3 | -- | 26 | 78 | -- | -- | -- | -- | -- |
Tanabe [24] | 2001 | 56.9 | -- | 19.6 | 21 | -- | -- | -- | 76.1 | -- |
Shen [25] | 2002 | 34.6 | -- | 22.4 | 20 | -- | -- | -- | -- | -- |
Minagawa [26] | 2003 | 54.7 | -- | 31 | 67 | 56/11 | 62.7 | 68.6 | 55.2 | 76.1 |
Chen [27] | 2004 | 56.5 | 9.0 | 11.8 | 34 | -- | -- | -- | -- | -- |
Sun [28] | 2005 | -- | 26.8 | -- | 57 | 52/5 | 52.3 | 85.9 | 82.4 | -- |
Kobayashi [29] | 2006 | 55.2 | -- | 29 | 60 | -- | -- | -- | -- | -- |
Tralhão [30] | 2007 | 40 | 27 | 21 | 16 | 14/2 | 61.3 | 93.7 | 43.7 | -- |
Itamoto [31] | 2007 | 58 | 22.4 | 25 | 84 | 64/20 | 66 | 67 | 63 | 63 |
Wu [32] | 2009 | 54.4 | 26.3 | 23.2 | 149 | 114/35 | 59�0 | -- | 79.1 | -- |
Kawano [33] | 2009 | 67.4 | 12 | 8.8 | 13 | -- | -- | -- | -- | -- |
Nagano [34] | 2009 | 45.5 | Â | 22.8 | 24 | 20/4 | 66.9 | -- | 37.5 | -- |
Liang [35] | 2008 | -- | Â | -- | 44 | 39/5 | 48.8 | -- | 77.2 | 59.0 |