Table 1 Comparison of clinicopathological features, operative procedures and perioperative outcomes between the initial hepatectomy group and the repeat resection group

Median age at operation (years)

49.0

52.0

NS

Gender (male/female)

419/43

32/5

NS

HBV-positive

451 (97.6)

37 (100)

NS

Child-Pugh class A

424 (91.8)

37 (100)

NS

Serum AFP > 100 ng/mL

212 (45.8)

13 (35.1)

NS

Total bilirubin (umol/L)

14.5 ± 8.9

16.4 ± 8.3

NS

Serum albumin (g/L)

41.8 ± 3.6

41.2 ± 3.7

NS

Serum ALT (IU/L)

56.3 ± 51.8

36.7 ± 11.4

0.028

Serum AST (IU/L)

53.4 ± 52.7

33.0 ± 10.1

0.007

Tumor size in diameter (cm)

7.3 ± 4.8

3.3 ± 1.9

<0.001

Tumor location

NS

   Right lobe

326 (70.5)

23 (62.1)

   Left lobe

134 (29.0)

14 (37.8)

   Both lobe

12 (2.5)

0

Cirrhotic liver

238 (51.6)

20 (54)

NS

Solitary tumor

374 (80.9)

28 (75.6)

NS

Tumor capsule formation

291 (62.9)

26 (70.2)

NS

Vascular invasion

272 (58.2)

19 (51.3)

NS

Edmonson-Steiner grade

NS

   G1-G2

31 (6.7)

4 (10.8)

   G3-G4

431 (93.3)

33 (89.2)

Extent of hepatectomy

0.018

   Major resection

133 (28.7)

4 (10.8)

   Minor resection

329 (56.8)

33 (89.2)

Combined organ resection

114 (24.6)

0

0.001

Operation time (min)

228.6 ± 68.4

211.8 ± 67.0

NS

Clamping time (min)

18.5 ± 8.2

16.7 ± 10.4

NS

Blood loss (mL)

690.0 ± 762.8

364.2 ± 293.4

0.002

Need for blood transfusion

64 (13.8)

6 (16.2)

NS

Postoperative complication

147 (31.8)

9 (24.3)

NS

Mortality

4 (0.8)

0

NS

Postoperative hospital stay (days)

10.6 ± 3.2

11.5 ± 3.1

NS