Table 2 Comparison of Intraoperative Inking Regimen with Standard Inking Regimen

Measurement

Intraoperative

(n = 26)

Standard

(n = 39)

P-value

1a. No. patients with positive/close margins at original surgery

6 (23%)

18 (46%)

0.06

4 (15%)

7 (18%)

4 (15%)

15 (38%)

1b. No. patients who underwent re-excision

5 (19%)

15 (38%)

0.16

†Re-excision lumpectomy

3 (12%)

11 (28%)

†Mastectomy

3 (12%)

6 (15%)

2. No. patients with residual disease identified on re-excision lumpectomy

2 of 3 (67%)

3 of 11 (27%)

0.5

3. Residual disease identified in the specific margins at re-excision lumpectomy

4 of 5 (80%)

4 of 20 (20%)

0.02

4a. No. patients with positive/close margins on original lumpectomy specimen alone

9 (35%)

22 (56%)

0.08

4b. No. patients with positive/close margins on original lumpectomy specimen who had extra margins taken at original surgery

5 of 9 (55%)

11 of 22 (50%)

0.78

4c. No. patients with positive/close margins on original lumpectomy specimen whose margins were cleared by extra margins taken at original surgery

3 of 9 (33%)

4 of 22 (18%)

0.36

5. No. extra margins taken at original surgery that corresponded to positive/close margins on original lumpectomy

6 of 7 (86%)

15 of 19 (79%)

0.70