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Table 2 Location and function of HERG channel.

From: Eag and HERG potassium channels as novel therapeutic targets in cancer

Organ

Function

References

Heart

Repolarisation of cardiac action potential

[21, 29, 30]

CNS

Maintain membrane potential and development of neurons of spinal cord and carotid glomus cells

[92, 93]

GIT

Regulate motility of gut

[94]

Endocrine system

Secretion of insulin and modulating epinephrine release in chromaffin cells

[95, 96]