Table 3 Previous studies evaluating the contralateral pelvic and paraaortic lymphatic metastasis presenting in unilateral clinical stage I or stage Ia epithelial ovarian carcinoma patients (stage Ia patients are bolded and ipsilateral pelvic metastasis are not included.).
Author | Description of Study and Stages | Tumor Laterality | Reported Histology and Grade (Gr) | CPLN or PA Met* | n |
|---|---|---|---|---|---|
Walter J. [5] | Ia (case report) | Left (Ia) | Anaplastic, Gr3 | Right paraaortic + right pelvic | 1 |
Onda [10] | 7 out of 33 Stage I patients have lymphatic metastasis. 6 have unilateral tumor. | Left | Not defined | Bilateral pelvic+PA | 1 |
Right | Right PA | 1 | |||
Right | Right pelvic+Right PA | 1 | |||
Right | Left pelvic+Bilateral PA | 1 | |||
Cass [10] | 96 unilateral stage I patients with unilateral or bilateral pelvic paraortic lymphadenectomy are evaluated. 14 of these 96 had lymphatic metastasis. | Right | Gr3 | Left PA | 1 |
Right | Gr3 | Left pelvic | 1 | ||
Left | Gr3 | Right PA +Right pelvic | 1 | ||
Left | Gr3 | Bilateral pelvic | 1 | ||
Right | Gr3 | Bilateral pelvic | 1 | ||
Right | Gr3 | Right PA | 4 | ||
Left | Gr3 | Left PA | 2 | ||
Petru [2] | 9 out of 40 Stage I patients had lymphatic metastasis. 6 out of 9 patients had unilateral tumors. | Not defined | Not defined | Contralateral pelvic | 1 |
Pelvic+paraaortic | 1 | ||||
Negishi[9] | 8 out of 123 stage I patients had lymphatic metastasis. One patient was stage Ia. | Right (Ia) | Clear cell (Both) | Right paraaortic | 2 |
Left | Clear cell (Both) | Bilateral PA | 2 | ||
Left | Mucinous (grade ?) | Bilateral pelvic and PA | 1 | ||
Left | Clear | Left PA | 1 | ||
Left | Mucinous | Left PA | 1 | ||
Left | Serous | Left PA | 1 | ||
Sakuragi [13] | 4 out of 78 Stage I patients had lymphatic metastasis. One patient out of 31 Stage Ia had lymphatic metastasis. | Right (Ia) | Clear cell Gr1 | Right PA | 1 |
Left | Clear/Mucinous Gr2 | Left PA | 2 | ||
Left | Clear cell Gr1 | Bilateral PA | 1 | ||
Morrice [15] | 8 out of 60 stage Ia patients had lymphatic metastasis. | Not defined | Gr2:4 | Contralateral PA | 1 |
Not defined | Gr3:3 | Ipsilateral PA | 5 | ||
Ipsilateral PA+Pelvic | 1 | ||||
Baiocchi, [20] | 32 out of 242 Stage I patients had lymphatic metastasis. 24 out of 32 was in Stage Ia. Total number of stage Ia was 215. | Right | Overall distribution | Left pelvic | 1 |
Right | of grades among | Left PA | 2 | ||
Right | patients with | Bilateral pelvic+PA | 3 | ||
Right | lymphatic metastasis | Right PA | 5 | ||
Right | was as follows: | Right pelvic+PA | 2 | ||
Left | Borderline: 7 | Left PA | 4 | ||
Gr1: 3 | |||||
Gr2: 6 | |||||
Gr3: 15 | |||||
Undefined: 1 | |||||
Suzuki [14] | 5 out of 47 Stage I patients had lymphatic metastasis. 18 patients had Stage Ia disease. | Not defined Ia | Clear cell Gr2 | Contralateral pelvic | 1 |
Not defined | Serous Gr1 | Contralateral pelvic | 1 | ||
Not defined | Serous Gr2 | Ipsilateral pelvic+PA | 1 | ||
Not defined | Serous Gr2 | PA | 1 | ||
Not defined | Serous Gr1 | Ipsilateral suprainguinal | 1 | ||
This Study | 2 out of 33 stage Ia patients had lymphatic metastasis | Left | Transitional Gr3 | PA | 1 |