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Table 1 Data of the patient collective and clinical course of the tumor disease.

From: Leiomyosarcoma of intravascular origin - a rare tumor entity: clinical pathological study of twelve cases

Patient

Age at the time of diag.

Localisation

Affected vessel

Size in cm

TNM

Comments

Thrombembolic event

Status

1

66

right upper extremity,

supra-clavicula region

internal Jugular vein/sub-clavian vein

7.6 × 8 × 3.3

T2 N0 M0

G2

second expert opinion

n

DOD

2

74

left thigh

femoral vein

-

--

no diagnosis before primary surgery

n

DOD

3

77

Left upper extremity, wrist

accompaniing ulna vein

2.7×1.7×1.2

T1 N0 M0

G1

initial surgery for a suspected wrist ganglion revealed the diagnosis of a intravascular leiomyosarcoma

n

alive

4

52

right thigh

femoral vein

6.4 × 7 × 9

T2 N0 M0

G3

palpable tumor 4 month before diagnosis

n

DOD

5

55

left dorsum of the upper arm

subcutaneous Vein

7.8 × 4.5 × 5

T2 N0 M0

G3

palpable tumor 2 month before diagnosis

n

alive

6

64

right thigh

subcutaineous vein

2.5 × 2 × 1

T1 N0 M0

G2

palpable tumor 3-4 month before diagnosis; external primary tumor enucliation

second expert opinion

n

alive

7

41

retro-peritoneum

inferior vena cava

8.8 × 6 × 5

T2 N0 M0

G1

primary histology Pathol. BG-Uni. Bergmannsheil Bochum; Second expert opinion Oncological resection

Dep. Visceral Surg. Uni Bochum

n

alive

8

56

right thigh

external iliac vein, femoral vein

10.1 × 7.5 × 5

T2 N0 M0

G2

3 tumor free lymph nodes in primary histology

Oncological resection Dep. Visceral Surg. Uni Bochum

deep vein throm-bosis

alive

9

61

left thigh

femoral vein

2.3 × 2 × 6

T2 N0 M0

G2

-

n

DOD

10

59

left thigh

femoral vein

9.6 × 6 × 4

T2 N0 M0

G3

Histology was reassessed after transferral due to a tumor relapse

pulmonary embo-lism

alive

11

44

left thigh

great saphenous vein

12 × 4 × 3.6

T2 N0 M1

(lung,

liver)

G3

palpable small tumor, suspected to be a lipoma two years prior to diagnosis

thrombophlebitis of the saphenous vein

alive

12

56

left lower leg

great sahpenous vein

5 × 4 × 1

T2N0

M1 (pulmo) G3

crossectomy

thrombophlebitis preop., paget shrotter syn-drome postop.

alive