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Figure 3 | World Journal of Surgical Oncology

Figure 3

From: Identification of a novel germ-line mutation in the TP53 gene in a Mexican family with Li-Fraumeni syndrome

Figure 3

DNA sequence showing the insertion and cDNA sequence generated by the mutation. A. Sequence analysis of TP53 exon 4 for the index patient. Bold underlined indicates the duplicated sequence, below which the wild-type sequence is shown. B. Changes in the cDNA sequence: new cDNA sequence (bold) and generation of a premature stop codon (italics). The 7 nucleotide insertion is underlined.

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World Journal of Surgical Oncology

ISSN: 1477-7819

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