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Table 1 Comparison of the results of IHC and FISH

From: Comparison of immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH) assessment for Her-2 status in breast cancer

IHC scoring Her-2 FISH amplified Her-2 FISH non-amplified Concordance by IHC Discordance by IHC
0 and 1+ (n = 26) 5 21 (21/26)80.8% (5/26)19.2%
2+ (n = 10) 7 3 (7/10)70.0% (3/10)30.0%
3+ (n = 14) 13 1 (13/14)92.9% (1/14)7.1%
  1. IHC = immunohistochemistry; FISH = fluorescence in situ hybridization