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Table 1 Comparison of the results of IHC and FISH

From: Comparison of immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH) assessment for Her-2 status in breast cancer

IHC scoring

Her-2 FISH amplified

Her-2 FISH non-amplified

Concordance by IHC

Discordance by IHC

0 and 1+ (n = 26)

5

21

(21/26)80.8%

(5/26)19.2%

2+ (n = 10)

7

3

(7/10)70.0%

(3/10)30.0%

3+ (n = 14)

13

1

(13/14)92.9%

(1/14)7.1%

  1. IHC = immunohistochemistry; FISH = fluorescence in situ hybridization