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Table 1 Patient and tumor demographics for invasive lobular carcinomas and invasive ductal carcinomas

From: Comparison of intraoperative frozen section analysis for sentinel lymph node biopsy during breast cancer surgery for invasive lobular carcinoma and invasive ductal carcinoma

  ILC (n = 131) IDC (n = 133) Total cases (n = 264) P-value
Age (years) 59 (35–87) 55 (24–82) 57 (24–87) 0.001
Tumor size (cm) 2.0 (0.2–9.0) 1.5 (0.1–6.5) 1.7 (0.1–9.0) 0.006
T-stage     
   T1 75(58%) 88 (66%) 163 (62%) 0.298
   T2 49 (38%) 43 (32%) 92 (35%)  
   T3 5 (4%) 2 (2%) 7 (3%)  
   T4 1 (1%) 0 (0%) 1 (0.5%)  
Tumor focality     
   Unifocal 97 (75%) 123 (93%) 220 (84%) <0.001
   Multifocal 19 (15%) 9 (7%) 28 (11%)  
   Multicentric 14 (11%) 1 (1%) 15 (6%)  
Histologic grade     
   Grade 1 40 (31%) 32 (24%) 72 (27%) <0.001
   Grade 2 57 (44%) 52 (39%) 109 (41%)  
   Grade 3 17 (13%) 48 (36%) 65 (25%)  
   Unknown 17 (13%) 1 (1%) 18 (7%)  
ER status     
   Positive 121 (93%) 96 (72%) 217 (82) <0.001
   Negative 2 (2%) 29 (22%) 31 (12%)  
   Unknown 8 (6%) 8 (6%) 16 (6%)  
PR status     
   Positive 108 (82%) 81 (61%) 189 (72%) <0.001
   Negative 16 (12%) 44 (33%) 60 (23%)  
   Unknown 7 (5%) 8 (6%) 15 (6%)  
Her-2/neu     
   Positive 13 (10%) 35 (26%) 48 (18%) 0.003
   Negative 106 (81%) 87 (65%) 193 (73%)  
   Unknown 12 (9%) 11 (8%) 23 (9%)  
LVI     
   Positive 20 (15%) 41 (31%) 61 (23%) 0.005
   Negative 109 (83%) 92 (69%) 201 (76%)  
   Unknown 2 (2%) 0 (0%) 2 (1%)  
  1. ILC, invasive lobular carcinoma; IDC, invasive ductal carcinoma; ER, estrogen receptor; PR, progesterone receptor; LVI, lymphovascular invasion