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Table 1 Historical timeline for milestones in radioguided surgery

From: A comprehensive overview of radioguided surgery using gamma detection probe technology

Year Milestone
1949 Selverstone et al [1] at Harvard Medical School (Boston, Massachusetts, USA) were the very first to report the concept of radioguided surgery using of a Geiger-Müller tube device and 32P to detect brain tumors.
1956 Harris et al [3] at the Oak Ridge Institute of Nuclear Studies Medical Hospital (Oak Ridge, Tennessee, USA) were the first to report the application of a gamma detection probe during radioguided surgery using 131I to detect residual thyroid tissue.
1981 Harvey et al [743] at Presbyterian Hospital of Dallas (Dallas, Texas, USA) first reported the application of a gamma detection probe for radioguided biopsy of benign and metastatic bone lesions using 99mTc methylene diphosphonate.
1981 Ghelman et al [728] at The Hospital for Special Surgery (New York, New York, USA) first reported the application of a gamma detection probe for radioguided resection of a benign bone lesion using 99mTc methylene diphosphonate.
1984 Aitken et al [289, 290] at The Ohio State University (Columbus, Ohio, USA) first reported radioimmunoguided surgery using 131I-labeled anti-CEA polyclonal antibody to detect colorectal cancer.
1984 Ubhi et al. [408] at Queen's Medical Center/University Hospital (Nottingham, England, UK) first reported radioguided surgery using 201Tl-thallous chloride for the detecting a parathyroid adenoma.
1987 Sickle-Santanello et al [299] at The Ohio State University (Columbus, Ohio, USA) first reported radioimmunoguided surgery using 125I-labeled anti-TAG-72 monoclonal antibody to detect colorectal cancer.
1993 Krag et al [135] at The University of Vermont (Burlington, Vermont, USA) first reported radioguided sentinel lymph node biopsy using 99mTc radiocolloid for breast cancer.
1993 Alex et al [188] at The University of Vermont (Burlington, Vermont, USA) first reported radioguided sentinel lymph node biopsy using 99mTc radiocolloid for malignant melanoma.
1995 Martinez et al [409] at The Ohio State University (Columbus, Ohio, USA) first reported use of 99mTc-MIBI for the detecting parathyroid gland pathology.
1997 Norman and Chheda [410] at The University of South Florida (Tampa, Florida, USA) popularized the technique of minimally-invasive radioguided surgery using 99mTc-MIBI for the surgical management of primary hyperparathyroidism.
1999 Desai et al [35, 36] at The Ohio State University (Columbus, Ohio, USA) first reported use of 18F-FDG-directed surgery in the surgical management of colorectal cancer.
2008 Strong et al [29] at Memorial Sloan-Kettering Cancer Center (New York, New York, USA) first reported radioimmunoguided surgery using 124I-labeled monoclonal antibody specific for clear cell renal cell cancer.