Figure 2
A and B) Photomicrograph showing malignant glands typical of adenocarcinoma lined by atypical cells with hyperchromatic nuclei. There is an increase in mitotic activity within the cells and the presence of necrotic material. Stained with haematoxylin & eosin. C) Immunohistochemistry with CK20 showing tumour cell cytoplasm stained. D) Immunohistochemistry with CDX2 staining showing prominent nuclei of tumour cells. CK20 and CDX2 are consistent with cells of colorectal origin. Note: Original magnifications a – d 20×.