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Table 1 Classification of PG

From: Pyoderma gangrenosum after totally implanted central venous access device insertion

Ulcerous PG The most common form is the ulcerous type. It is rapidly progressive, severely painful and characterized by a necrolytic, mucopurulent deep ulcer with an undermined, violaceous, oedematous livid border. PG ulcer is a dynamic process, rapidly destroying skin tissue, producing a liquefactive necrosis. It is associated with arthritis (37%), IBD (30%), hematological malignancies, multiple myeloma, paraproteinema and other conditions. Aggressive immunosuppressant treatment is indispensable.
Pustulous PG Pustulous PG is characterized by multiple lesions with inflammatory borders. It is strongly associated with IBD. Upon remission of IBD, skin lesions also improve.
Vegetans PG Vegetans PG is solitary, slowly progressive form of PG, characterized by superficial ulcerations with defined borders, sometimes presenting exophytic growth. Less aggressive systemic or topical treatment is usually sufficient.
Bullous PG Bullous PG is characterized by painful superficial bullae with progressive ulceration and erythematous borders. It is associated with myeloproliferative syndromes and has a poor prognosis if associated with leukemia. Systemic immunosuppression is necessary.