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Table 2 Comparison of deduced amino acid sequences in the LMP1 exon 3 in NPC1 and NPC2

From: Epstein-Barr virus latent membrane protein-1 (LMP-1) 30-bp deletion and Xho I-loss is associated with type III nasopharyngeal carcinoma in Malaysia

Nucleotide

168342

Codon

327

328

329

330

331

332

333

334

335

336

337

338

339

340

341

342

343

344

345

B95.8

V

E

N

K

G

G

D

Q

G

P

P

L

M

T

D

G

G

G

G

CAO

 

A

     

R

   

S

       

China I

       

R

D

  

S

       

NPC 1

       

R

   

S

       

NPC 2

       

R

D

  

S

       

Nucleotide

168342

Codon

346

347

348

349

350

351

352

353

354

355

356

357

358

359

360

361

362

363

364

B95.8

H

S

H

D

S

G

H

G

G

G

D

P

H

L

P

T

L

L

L

CAO

*

*

*

*

*

*

             

China I

*

*

*

*

*

*

             

NPC 1

*

*

*

*

*

*

             

NPC 2

*

*

*

*

*

*

             

Nucleotide

168342

Codon

365

366

367

368

369

370

371

372

373

374

375

376

377

378

379

380

381

382

383

B95.8

G

S

S

G

S

G

G

D

D

D

D

P

H

G

P

V

Q

L

S

CAO

 

T

                 

China I

 

T

                 

NPC 1

 

T

                 

NPC 2

 

T

                 
  1. Asterisks (*) indicate amino acid deletion. Previously published prototype sequences were obtained from Fennewald et al., 1984 (B95.8).
  2. Hu et al., 1991 (CAO), Sung et al., 1998 (China 1). NPC 1 and NPC 2 are isolates from NPC tissue samples subjected to DNA sequencing.
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World Journal of Surgical Oncology

ISSN: 1477-7819

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