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Table 2 Comparison of deduced amino acid sequences in the LMP1 exon 3 in NPC1 and NPC2

From: Epstein-Barr virus latent membrane protein-1 (LMP-1) 30-bp deletion and Xho I-loss is associated with type III nasopharyngeal carcinoma in Malaysia

Nucleotide 168342
Codon 327 328 329 330 331 332 333 334 335 336 337 338 339 340 341 342 343 344 345
B95.8 V E N K G G D Q G P P L M T D G G G G
CAO   A       R     S        
China I         R D    S        
NPC 1         R     S        
NPC 2         R D    S        
Nucleotide 168342
Codon 346 347 348 349 350 351 352 353 354 355 356 357 358 359 360 361 362 363 364
B95.8 H S H D S G H G G G D P H L P T L L L
CAO * * * * * *              
China I * * * * * *              
NPC 1 * * * * * *              
NPC 2 * * * * * *              
Nucleotide 168342
Codon 365 366 367 368 369 370 371 372 373 374 375 376 377 378 379 380 381 382 383
B95.8 G S S G S G G D D D D P H G P V Q L S
CAO   T                  
China I   T                  
NPC 1   T                  
NPC 2   T                  
  1. Asterisks (*) indicate amino acid deletion. Previously published prototype sequences were obtained from Fennewald et al., 1984 (B95.8).
  2. Hu et al., 1991 (CAO), Sung et al., 1998 (China 1). NPC 1 and NPC 2 are isolates from NPC tissue samples subjected to DNA sequencing.