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Table 1 30-bp deletion and Xho I polymorphism in NPC biopsies and plasma, and non-malignant nasopharyngeal tissues

From: Epstein-Barr virus latent membrane protein-1 (LMP-1) 30-bp deletion and Xho I-loss is associated with type III nasopharyngeal carcinoma in Malaysia

 

NPC tissues % (n = 42)

Non-malignant nasopharyngeal tissues % (n = 10)

NPC plasma % (n = 35)

Analysis

   

LMP1 30-bp deletion

   

   Frequency detected by PCR

81.0 (34/42)

80 (8/10)

82.9 (29/35)

With deletion

55.9 (19/34)

0

24.1 (7/29)

No deletion

44.1 (15/34)

100 (8/8)

75.9 (22/29)

With and without deletion

0 (0/34)

0 (0/8)

17.2 (5/29)

Xho I polymorphism

   

   Frequency detected by PCR

92.9 (39/42)

80 (8/10)

85.7 (30/35)

Loss of Xho I site

87.2 (34/39)

0

36.7 (11/30)

Retention of Xho I site

12.8 (5/39)

100 (8/8)

63.3 (19/30)

Co-existence of 30-bp deletion and Xho I-loss

59.4 (19/32)

0 (0/8)

25.0 (6/24)