Figure 2
From: A rare tumoral combination, synchronous lung adenocarcinoma and mantle cell lymphoma of the pleura
Lung adenocarcinoma with micropapillary pattern (A, E & H). Neoplastic ducts showing strong nuclear staining for TTF-1 (B) and cytokeratin 7 (C). Mantle cell lymphoma with diffuse infiltration of the pleura (D, E & H). Lymphomatous cells, positive for CD5 (E) and cyclin D1 (F). FISH method using the LSI IGH/CCND1 dual color, dual fusion translocation probe: nucleus of neoplastic lymphoid cell with t(11;14) displaying the signal pattern 2 yellow (fusion translocation signals), 2 red (CCND1 gene) and 2 green (IGH gene) (G).