10 mm, lymph-vascular space involvement, tumor diameter > 17.5 mm, and parametrial involvement. Postoperative treatment was significantly more frequent in patients with "abundant" vascularization (OR: 20.8, 95% CIs: 2 to 211). The presence of scanty-moderate vascularization with a PI < 0.82 or abundant vascularization with either PI > 0.82 or PI < 0.82 was associated with high-risk group in 94.4% of the cases (OR: 21.2, 95% CI: 1.9 to 236.0) Conclusion The results are consistent with a relationship between tumor angiogenesis and prognostic factors for recurrence in early cervical cancer. "Abundant" vascularization and PI < 0.82 may be related to postoperative treatment due to risk factors."/>
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Table 1 Patients' characteristics

From: Neoangiogenesis in early cervical cancer: Correlation between color Doppler findings and risk factors. A prospective observational study

  n %
FIGO Stage   
Ia2 1 3.7
Ib1 25 92.6
IIa 1 3.7
Tumor size (cm)* 2.2 (1–3.9)
Histology   
SCC 18 66.7
Non-SCC 9 33.3
Grade 1 11 40.7
Grade 2 13 48.1
Grade 3 3 11.1
Surgery   
RH-II 22 81.5
RH-III 5 18.5
PLND** 14 (4–37)
+ 5 18.5
-- 22 81.4
DSI (mm) < 10 8 29.6
DSI > 10 mm 19 70.4
LVSI+ 9 33.3
LVSI- 17 62.9
LVSI Unknown 1 3.7
Postop. Treat.   
EPRT + Brachitherapy 11 40.7
Chemoradiation 7 25.9
   No 9 33.3
  1. *mean, range in parentheses ** median, range in parentheses
  2. SCC = Squamous cell carcinoma. RH = radical hysterectomy. PLND = Pelvic Lymph node dissection. DSI = Depth stromal invasion. LVSI = Lymph-vascualr space invasion. EPRT = External pelvic radiation