Table 2 Relationship between expression of the differents MMPs and TIMPs in the cells.
Factor | EvenT frecuency | Tes Mc Nemar ≠ Degree of ASSOCIATION |
|---|---|---|
MMP-1 | ||
Epithelium (-) vs (+) | 9/11 | P = 0.004 tumor ≠ epithelium |
Tumor (-) vs (+) | 0/20 | P = 0.000 tumor ≠ endothelium |
Stroma (-) vs (+) | 3/17 | |
Endothelium (-) vs (+) | 18/2 | |
MMP-2 | ||
Epithelium (-) vs (+) | 9/11 | P = 0.031 tumor ≠ stroma |
Tumor (-) vs (+) | 7/13 | P = 0.001 tumor ≠ endothelium |
Stroma (-) vs (+) | 13/7 | |
Endothelium (-) vs (+) | 18/2 | |
MMP-3 | ||
Epithelium (-) vs (+) | 11/9 | P = 0.004 tumor ≠ endothelium |
Tumor (-) vs (+) | 10/10 | |
Stroma (-) vs (+) | 11/9 | |
Endothelium (-) vs (+) | 19/1 | |
MMP-9 | ||
Epithelium (-) vs (+) | 17/3 | P = 0.031 tumor ≠ endothelium |
Tumor (-) vs (+) | 14/6 | |
Stroma (-) vs (+) | 16/4 | |
Endothelium (-) vs (+) | 20/0 | |
MMP-11 | ||
Epithelium (-) vs (+) | 8/12 | P = 0.039 tumor ≠ stroma |
Tumor (-) vs (+) | 1/19 | P = 0.039 tumor ≠ epithelium |
Stroma (-) vs (+) | 8/12 | P = 0.000 tumor ≠ endothelium |
Endothelium (-) vs (+) | 16/4 | |
MMP-13 | ||
Epithelium (-) vs (+) | 12/8 | P = 0.031 tumor ≠ endothelium |
Tumor (-) vs (+) | 14/6 | |
Stroma (-) vs (+) | 14/6 | |
Endothelium (-) vs (+) | 20/0 | |
TIMP-1 | ||
Epithelium (-) vs (+) | 8/12 | P = 0.002 tumor ≠ stroma |
Tumor (-) vs (+) | 19/1 | P = 0.039 tumor ≠ epithelium |
Stroma (-) vs (+) | 11/9 | P = 0.000 tumor ≠ endothelium |
Endothelium (-) vs (+) | 16/4 | |
TIMP-2 | ||
Epithelium (-) vs (+) | 17/3 | |
Tumor (-) vs (+) | 18/2 | |
Stroma (-) vs (+) | 16/4 | |
Endothelium (-) vs (+) | 20/0 | |
MMP-2 vs TIMP-2(+) vs (+) | 13/2 | P = 0.007 |
MMP-9 vs TIMP-1(+) vs (+) | 6/1 | P = 0.001 |