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Table 4 Correlation of HER-2, ER and PR status with clinicopathological data

From: Correlation of HER-2 over-expression with clinico-pathological parameters in Tunisian breast carcinoma

 

HER-2 over-expression

ER Positive

PR Positive

 

n (%)

p

n (%)

p

n (%)

p

Age

 

0.28

 

0.002

 

0. 76

   ≤ 50 years

17 (21.3)

 

38 (47.5)

 

43 (53.8)

 

   > 50 years

11 (14.7)

 

54 (72)

 

38 (51.4)

 

Tumor size

 

0.104

 

0.129

 

0.72

   ≤ 5 cm

18 (15.3)

 

74 (62.7)

 

63 (53.4)

 

   > 5 cm

10 (27)

 

18 (48.6)

 

18 (50)

 

Histologic type

 

0.33

 

0.31

 

0.47

   Ductal

22 (16.8)

 

80 (61.1)

 

70 (53.8)

 

   Non ductal

6 (25)

 

12 (50)

 

11 (45.8)

 

Lymph-node

 

0.000

 

0.88

 

0.66

   Negative

4 (4,4)

 

53 (58.9)

 

46 (51.1)

 

   Positive

24 (36.9)

 

39 (60)

 

35 (54.7)

 

Tumor Grade

 

0.072

 

0.000

 

0.000

   1–2

17 (14.8)

 

83 (72.2)

 

70 (61.4)

 

   3

11 (27.5)

 

9 (22.5)

 

11 (27.5)

 
  1. HER-2: Human epidermal growth factor receptor 2; ER: Estrogen receptor; PR: Progesterone receptor.